Geminiviruses

Multitasking in replication is common among geminiviruses.

Geminiviruses package single-stranded circular DNA and replicate via double-stranded DNA intermediates. During the past decade, increasing evidence has led to the general acceptance that their replication follows a rolling-circle replication mechanism like bacteriophages with single-stranded DNA. In a recent study, we showed that this is also true for Abutilon mosaic geminivirus (AbMV), but tha...

Whiteflies: vectors, and victims (?), of geminiviruses.

Autophagy functions as an antiviral mechanism against geminiviruses in plants

Autophagy is an evolutionarily conserved process that recycles damaged or unwanted cellular components, and has been linked to plant immunity. However, how autophagy contributes to plant immunity is unknown. Here we reported that the plant autophagic machinery targets the virulence factor βC1 of Cotton leaf curl Multan virus (CLCuMuV) for degradation through its interaction with the key autopha...

Conventional breeding for resistance to whitefly-transmitted geminiviruses

The whitefly Bemisia tabaci Genn. is a pervasive pest and vector of plant viruses. The existence of B. tabaci biotypes and numerous whitefly-transmitted geminiviruses (begomoviruses) affecting food and industrial crops, has become a major constraint to agricultural development in tropical and subtropical regions of the world. The predominant whitefly and begomovirus method of control has been t...

DNA replication and cell cycle in plants: learning from geminiviruses.

Plant cell growth and development depend on continuous cell proliferation which is restricted to small regions of the plant called meristems. Infection by geminiviruses, small DNA viruses whose replicative cycle relies on host cell factors, is excluded from those proliferating areas. Since most of the replicative factors are present, almost exclusively, in proliferating cells, geminivirus infec...